### Changes in UGENE v. 48

- Improved macOS support: Dozens of minor interface issues have been fixed.
- Revamped interface for working with restriction sites: New filters and enzyme details have been added.
- Most external tools shipped with UGENE have been updated to their latest versions.
- Enhanced support for PDB and ClustalW file formats.
- Many small issues related to the usability and stability of UGENE on all platforms have been fixed.

A complete list of changes can be found on the UGENE web site.