libusb-1.0 is an almost-rewrite of the previous stable branch, libusb-0.1. It is a lightweight library that can be efficiently integrated into applications of any kind, with several new features. Backwards compatibility libusb-1.0 is not backwards compatible with libusb-0.1 - all function names are different, etc. However, libusb-1.0 is designed to be happily installable alongside libusb-0.1 (even in the default configuration) so the lack of backwards compatibility is not really a problem - users can have both libusb versions present on the same system without conflict. That said, a libusb-compat-0.1 compatibility layer does exist. This is a "wrapper" which converts libusb-0.1 function calls to their 1.0 equivalents. For more info, see LibusbCompat0.1.