You'll need to add the following lines to /etc/rc.d/rc.local: # Start vboxadd if [ -x /etc/rc.d/rc.vboxadd ]; then /etc/rc.d/rc.vboxadd start fi # Start vboxadd-service if [ -x /etc/rc.d/rc.vboxadd-service ]; then /etc/rc.d/rc.vboxadd-service start fi This will load the support kernel module and will setup the network configuration for VirtualBox. You should then add the following to /etc/rc.d/rc.local_shutdown: # Stop vboxadd if [ -x /etc/rc.d/rc.vboxadd ]; then /etc/rc.d/rc.vboxadd stop fi # Stop vboxadd-service if [ -x /etc/rc.d/rc.vboxadd-service ]; then /etc/rc.d/rc.vboxadd-service stop fi You might want to add "/usr/bin/VBoxClient" to your xinitrc file if you use a desktop environment that doesn't respect /etc/xdg/autostart or /usr/share/autostart