SeaView is a multiplatform, graphical user interface for multiple sequence alignment and molecular phylogeny. Features: - Reads and writes various file formats (NEXUS, MSF, CLUSTAL, FASTA, PHYLIP, MASE, Newick) of DNA and protein sequences and of phylogenetic trees. - Drives programs muscle or Clustal Omega for multiple sequence alignment, and also allows to use any external alignment algorithm able to read and write FASTA-formatted files. - Drives the Gblocks program to select blocks of evolutionarily conserved sites. - Computes phylogenetic trees by parsimony, using PHYLIP's dnapars / protpars algorithm, distance, with NJ or BioNJ algorithms on a variety of evolutionary distances, maximum likelihood, driving program PhyML - Can use the Transfer Bootstrap Expectation method to compute the bootstrap support of PhyML and distance trees. - Uses the Treerecs method to reconcile gene and species trees. - Prints and draws phylogenetic trees on screen, SVG, PDF or PostScript files. - Allows to download sequences from EMBL / GenBank / UniProt. For details and citation: Gouy M., Guindon S. & Gascuel O. (2010) SeaView version 4 : a multiplatform graphical user interface for sequence alignment and phylogenetic tree building. Molecular Biology and Evolution 27(2):221-224.